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Exploring the role of the phage-specific insert of bacteriophage Φ11 dUTPase K Nyíri, V Papp-Kádár, JE Szabó, V Németh, BG Vértessy Structural Chemistry 26 (5-6), 1425-1432		2015
Structural characterization of a complex derived from lead (II) perchlorate and acridono-18-crown-6 ether T Németh, Á Golcs, I Leveles, T Tóth, BG Vértessy, P Huszthy Structural Chemistry 26 (5-6), 1467-1471		2015
Cover Picture: Phenylalanine Ammonia‐Lyase‐Catalyzed Deamination of an Acyclic Amino Acid: Enzyme Mechanistic Studies Aided by a Novel Microreactor Filled with Magnetic Nanoparticles (ChemBioChem 16/2015) D Weiser, LC Bencze, G Bánóczi, F Ender, R Kiss, E Kókai, A Szilágyi, ... ChemBioChem 16 (16), 2257-2257		2015
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Structural biology and regulation of protein import into the nucleus M Christie, CW Chang, G Róna, KM Smith, AG Stewart, AAS Takeda, ... Journal of molecular biology		2015
Detection of uracil within DNA using a sensitive labeling method for in vitro and cellular applications G Róna, I Scheer, K Nagy, HL Pálinkás, G Tihanyi, M Borsos, A Békési, ... Nucleic acids research, gkv977		2015
Evidence-based structural model of the Staphylococcal repressor protein: separation of functions into different domains K Nyíri, B Kőhegyi, A Micsonai, J Kardos, BG Vertessy PloS one 10 (9), e0139086	1	2015
Life without dUTPase C Kerepesi, JE Szabó, V Grolmusz, BG Vértessy arXiv preprint arXiv:1509.04850		2015
Cross-species inhibition of dUTPase via the Staphylococcal Stl protein perturbs dNTP pool and colony formation in Mycobacterium R Hirmondó, JE Szabó, K Nyíri, S Tarjányi, P Dobrotka, J Tóth, ... DNA repair 30, 21-27	2	2015
Molecular mechanism for the thermo-sensitive phenotype of CHO-MT58 cell line harbouring a mutant CTP: phosphocholine cytidylyltransferase L Marton, GN Nagy, O Ozohanics, A Lábas, B Krámos, J Oláh, K Vékey, ... PloS one 10 (6), e0129632	1	2015
Mutations decouple proton transfer from phosphate cleavage in the dUTPase catalytic reaction A Lopata, PG Jambrina, PK Sharma, BR Brooks, J Toth, BG Vertessy, ... ACS Catalysis 5, 3225-3237		2015
Immobilization of Phenylalanine Ammonia‐Lyase on Single‐Walled Carbon Nanotubes for Stereoselective Biotransformations in Batch and Continuous‐Flow Modes JH Bartha‐Vári, MI Toşa, FD Irimie, D Weiser, Z Boros, BG Vértessy, ... ChemCatChem 7 (7), 1122-1128	1	2015
dUTPase expression correlates with cell division potential in Drosophila melanogaster A Horváth, J Batki, L Henn, T Lukacsovich, G Róna, M Erdélyi, ... FEBS Journal		2015
Antimycobacterial activity of peptide conjugate of pyridopyrimidine derivative against Mycobacterium tuberculosis in a series of in vitro and in vivo models K Horváti, B Bacsa, N Szabó, K Fodor, G Balka, M Rusvai, É Kiss, G Mező, ... Tuberculosis	1	2015
NLS copy‐number variation governs efficiency of nuclear import–case study on dUTPases G Róna, HL Pálinkás, M Borsos, A Horváth, I Scheer, A Benedek, ... FEBS Journal 281 (24), 5463-5478	2	2014
Composite Aromatic Boxes for Enzymatic Transformations of Quaternary Ammonium Substrates GN Nagy, L Marton, A Contet, O Ozohanics, LM Ardelean, Á Révész, ... Angewandte Chemie 126 (49), 13689-13694	4	2014
Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation G Róna, M Borsos, JJ Ellis, AM Mehdi, M Christie, Z Környei, M Neubrandt, ... Cell Cycle 13 (22), 3551-3564	5	2014
Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control JE Szabó, V Németh, V Papp-Kádár, K Nyíri, I Leveles, ÁÁ Bendes, ... Nucleic acids research 42 (19), 11912-11920	6	2014
Factors influencing nucleo-cytoplasmic trafficking: which matter? Response to Alvisi & Jans' comment on Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights G Róna, M Borsos, B Kobe, BG Vértessy Acta Crystallographica Section D: Biological Crystallography 70 (10), 2777-2778		2014
CHO-MT58: a model system for functionality studies of Plasmodium falciparum CTP: phosphocholine cytidylyltransferase L Marton, GN Nagy, N Kucsma, G Szakacs, B Vertessy FEBS JOURNAL 281, 553-553		2014
Insights into the catalytic mechanism of PfECT by thermodynamic, kinetic and structural analyses A Contet, S Maheshwari, E Pihan, GN Nagy, B Vertessy, D Douguet, ... FEBS JOURNAL 281, 574-575		2014
Preventive DNA repair by sanitizing the cellular (deoxy) nucleoside triphosphate pool GN Nagy, I Leveles, BG Vértessy FEBS Journal 281 (18), 4207-4223	8	2014
The metagenomic telescope B Szalkai, I Scheer, K Nagy, BG Vertessy, V Grolmusz	1	2014
Bisepoxide Cross‐Linked Enzyme Aggregates—New Immobilized Biocatalysts for Selective Biotransformations D Weiser, A Varga, K Kovács, F Nagy, A Szilágyi, BG Vértessy, C Paizs, ... ChemCatChem 6 (5), 1463-1469	5	2014
Secondary structure prediction of protein constructs using random incremental truncation and vacuum-ultraviolet CD spectroscopy M Pukáncsik, A Orbán, K Matsuo, K Gekko, D Hart, I Kézsmárki, ... arXiv preprint arXiv:1401.7362		2014
Expression and properties of the highly alkalophilic phenylalanine ammonia-lyase of thermophilic Rubrobacter xylanophilus K Kovacs, G Banoczi, A Varga, I Szabo, A Holczinger, G Hornyanszky, ...	5	2014
A preventív DNS-hibajavítás szerkezeti biológiája G Vértessy MAGYAR KÉMIAI FOLYÓIRAT-KÉMIAI KÖZLEMÉNYEK 120 (4), 176-177		2014
Structure and enzymatic mechanism of a moonlighting dUTPase I Leveles, V Németh, JE Szabo, V Harmat, K Nyiri, ÁÁ Bendes, ... Acta Crystallographica Section D: Biological Crystallography 69 (12), 2298-2308	5	2013
Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights G Róna, M Marfori, M Borsos, I Scheer, E Takács, J Tóth, F Babos, ... Acta Crystallographica Section D: Biological Crystallography 69 (12), 2495-2505	12	2013
Catalytic mechanism of α-phosphate attack in dUTPase is revealed by X-ray crystallographic snapshots of distinct intermediates, 31P-NMR spectroscopy and reaction path modelling O Barabás, V Németh, A Bodor, A Perczel, E Rosta, Z Kele, I Zagyva, ... Nucleic acids research 41 (22), 10542-10555	5	2013
Investigations of homologous disaccharides by elastic incoherent neutron scattering and wavelet multiresolution analysis S Magazù, F Migliardo, BG Vertessy, MT Caccamo Chemical Physics 424, 56-61	1	2013
Protein dynamics by neutron scattering: The protein dynamical transition and the fragile-to-strong dynamical crossover in hydrated lysozyme S Magazù, F Migliardo, A Benedetto, B Vertessy Chemical Physics 424, 26-31	2	2013
Genomic integrity of virulence genes is preserved by a dUTPase-based molecular switch J Szabo, V Nemeth, V Papp-Kadar, K Nyiri, I Leveles, A Bendes, ... EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 42, S134-S134		2013
Evolutionary and mechanistic insights into substrate and product accommodation of CTP: phosphocholine cytidylyltransferase from Plasmodium falciparum GN Nagy, L Marton, B Krámos, J Oláh, Á Révész, K Vékey, F Delsuc, ... FEBS Journal 280 (13), 3132-3148	8	2013
Malaria pigment crystals as magnetic micro-rotors: key for high-sensitivity diagnosis A Butykai, A Orbán, V Kocsis, D Szaller, S Bordács, E Tátrai-Szekeres, ... Scientific reports 3	21	2013
Nanomechanics of the MPMV Capsid-Protein-Binding RNA Fragment M Simon, Z Martonfalvi, P Bianco, B Vertessy, MSZ Kellermayer Biophysical Journal 104 (2), 168a-169a		2013
Silicon carbide quantum dots for bioimaging D Beke, Z Szekrényes, D Pálfi, G Róna, I Balogh, PA Maák, G Katona, ... Journal of Materials Research 28 (02), 205-209	15	2013
Egy tudományos hungarikum: a fluktuációs fit F Orosz, G Vértessy Magyar Tudomány 174 (2), 170-175		2013
An inter-species landscape of DNA repair proteins based on extreme metagenomes and repeated HMM profiling V Grolmusz, B Szalkai, G Vértessy, I Scher FEBS Journal 280 (Supl 1), 66		2013
dUTPase based switch controls transfer of virulence genes in order to preserve integrity of the transferred mobile genetic elements JE Szabó, V Németh-Pongrácz, V Papp-Kádár, K Nyíri, B Besztercei, ... FEBS Journal 280 (Supl 1), 59-60		2013
The impact of dUTPase expression on genome integrity A Horváth, J Batki, V Muha, G Róna, P Vilmos, M Erdélyi, G Vértessy FEBS Journal 280 (Supl 1), 58-59		2013
Molecular cloning and characterization of a thermostable esterase/lipase produced by a novel Anoxybacillus flavithermus strain L Chiş, F Hriscu, M, Bica, A, Toşa, M, Nagy, Gergely, Róna J Gen Appl Microbiol. 59 (2), 119-134	1	2013
Expanding the DNA alphabet in the fruit fly: Uracil enrichment in genomic DNA A Horváth, A Békési, V Muha, M Erdélyi, BG Vértessy Fly 7 (1), 23-27	1	2013
Molecular Mechanisms of Survival Strategies in Extreme Conditions S Magazù, F Migliardo, MA Gonzalez, C Mondelli, SF Parker, BG Vertessy Life 2 (4), 364-376		2012
Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvement V Muha, A Horváth, A Békési, M Pukáncsik, B Hodoscsek, G Merényi, ... PLoS Genet 8 (6), e1002738-e1002738	26	2012
The dUTPase enzyme is essential in Mycobacterium smegmatis I Pecsi, R Hirmondo, AC Brown, A Lopata, T Parish, BG Vertessy, J Tóth PLoS One 7 (5)	23	2012
Enhanced cellular uptake of a new, in silico identified antitubercular candidate by peptide conjugation K Horváti, B Bacsa, N Szabó, S Dávid, G Mező, V Grolmusz, B Vértessy, ... Bioconjugate chemistry 23 (5), 900-907	11	2012
Preparation of unnatural amino acids with ammonia-lyases and 2, 3-aminomutases L Poppe, C Paizs, K Kovács, FD Irimie, B Vértessy Unnatural Amino Acids, 3-19	5	2012
Discovery of novel MDR-Mycobacterium tuberculosis inhibitor by new FRIGATE computational screen C Scheich, Z Szabadka, B Vértessy, V Pütter, V Grolmusz, M Schade PloS one 6 (12), e28428	6	2011
Crystallization and preliminary crystallographic analysis of dUTPase from the ϕ11 helper phage of Staphylococcus aureus I Leveles, G Róna, I Zagyva, A Bendes, V Harmat, BG Vértessy Acta Crystallographica Section F: Structural Biology and Crystallization ...	9	2011
One-step method for quantitative determination of uracil in DNA by real-time PCR BG Vertessy, A Horvath, V Grolmusz US Patent App. 13/237,987		2011
Nucleotide pyrophosphatase employs a P-loop-like motif to enhance catalytic power and NDP/NTP discrimination I Pécsi, JE Szabó, SD Adams, I Simon, JR Sellers, BG Vértessy, J Tóth Proceedings of the National Academy of Sciences 108 (35), 14437-14442	16	2011
Nanomechanical manipulation of Mason-Pfizer monkey retroviral RNA fragment with optical tweezers M Simon, Z Martonfalvi, P Bianco, B Vertessy, M Kellermayer EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 40, 223-223	1	2011
Proteins with complex architecture as potential targets for drug design: a case study of Mycobacterium tuberculosis B Mészáros, J Tóth, BG Vértessy, Z Dosztányi, I Simon PLoS Comput Biol 7 (7), e1002118	17	2011
Cellular response to efficient dUTPase RNAi silencing in stable HeLa cell lines perturbs expression levels of genes involved in thymidylate metabolism G Merényi, J Kovári, J Tóth, E Takács, I Zagyva, A Erdei, BG Vértessy Nucleosides, Nucleotides and Nucleic Acids 30 (6), 369-390	12	2011
Calpain-catalyzed proteolysis of human dUTPase specifically removes the nuclear localization signal peptide Z Bozóky, G Róna, É Klement, KF Medzihradszky, G Merényi, ...	4	2011
Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans P Erdélyi, É Borsos, K Takács-Vellai, T Kovács, AL Kovács, T Sigmond, ... Journal of cell science 124 (9), 1510-1518	20	2011
Humán dUTPáz: kooperativitás és sejtbeli kölcsönhatások= Human dUTPase: cooperativity and cellular interactions G Vértessy, O Barabás, A Horváth, A Málnási Csizmadia, V Németh, ... OTKA Kutatási Jelentések\| OTKA Research Reports		2011
Association of RNA with the uracil‐DNA‐degrading factor has major conformational effects and is potentially involved in protein folding A Bekesi, M Pukancsik, P Haasz, L Felfoldi, I Leveles, V Muha, ... FEBS journal 278 (2), 295-315	4	2011
From “fluctuation fit” to “conformational selection”: evolution, rediscovery, and integration of a concept BG Vertessy, F Orosz Bioessays 33 (1), 30-34	21	2011
EXPRESSION OF PHENYLALANINE AMMONIA-LYASES IN ESCHERICHIA COLI STRAINS. K Kovács, A Holczinger, B Vértessy, L Poppe Studia Universitatis Babes-Bolyai, Chemia	1	2010
A one-step method for quantitative determination of uracil in DNA by real-time PCR A Horváth, BG Vértessy Nucleic acids research 38 (21), e196-e196	12	2010
Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase I Pecsi, I Leveles, V Harmat, BG Vertessy, J Toth Nucleic acids research 38 (20), 7179-7186	27	2010
Structure and mechanism of calmodulin binding to a signaling sphingolipid reveal new aspects of lipid-protein interactions E Kovacs, V Harmat, J Tóth, BG Vértessy, K Módos, J Kardos, K Liliom The FASEB Journal 24 (10), 3829-3839	4	2010
Sphingosylphosphorylcholine Binds to Calmodulin and Inhibits Its Function E Kovacs, V Harmat, J Toth, B Vertessy, K Modos, J Kardos, K LILIOM NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 382, 20-20		2010
Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases E Takács, G Nagy, I Leveles, V Harmat, A Lopata, J Tóth, BG Vértessy FEBS letters 584 (14), 3047-3054	8	2010
Drosophila proteins involved in metabolism of uracil‐DNA possess different types of nuclear localization signals G Merényi, E Kónya, BG Vértessy FEBS journal 277 (9), 2142-2156	6	2010
Physiological truncation and domain organization of a novel uracil‐DNA‐degrading factor M Pukáncsik, A Békési, É Klement, É Hunyadi‐Gulyás, KF Medzihradszky, ... FEBS journal 277 (5), 1245-1259	4	2010
Study of solvent–protein coupling effects by neutron scattering B Varga, F Migliardo, E Takacs, B Vertessy, S Magazù, MTF Telling Journal of biological physics 36 (2), 207-220	9	2010
The Role of P-loop in the Enzymatic Mechanism of Nucleotide Pyrophosphatases I Pecsi, JE Szabo, BG Vertessy, J Toth Biophysical Journal 98 (3), 449a	1	2010
Phosphorylation Dependent Nuclear Transport of Human Dutpase G Rona, E Takacs, Z Bozoky, Z Kornyei, M Neubrandt, J Toth, I Scheer, ... Biophysical Journal 98 (3), 309a		2010
Peculiar Regulatory Role of Magnesium in Nucleotide Hydrolysis of dUTPases E Takacs, BG Vertessy, J Toth Biophysical Journal 98 (3), 451a		2010
New Aspects of Lipid-Protein Interactions Revealed by Calmodulin Binding to the Lipid Mediator Sphingosylphosphorylcholine E Kovacs, V Harmat, J Toth, BG Vertessy, K Modos, J Kardos, K Liliom Biophysical Journal 98 (3), 675a		2010
Dissociation of Calmodulin-Target Peptide Complexes by the Lipid Mediator Sphingosylphosphorylcholine IMPLICATIONS IN CALCIUM SIGNALING E Kovacs, J Tóth, BG Vértessy, K Liliom Journal of Biological Chemistry 285 (3), 1799-1808	3	2010
Ansari MA, 341 Arnold U, 331 Arora A, 341 RG Atkinson, W Becker, F Beisson, A Bekesi, H Benyamini, A Bergemann, ... FEBS Journal 278, 401		2010
Nuclear localization signal-dependent and-independent movements of Drosophila melanogaster dUTPase isoforms during nuclear cleavage V Muha, I Zagyva, Z Venkei, J Szabad, BG Vértessy Biochemical and biophysical research communications 381 (2), 271-275	11	2009
Molecular shape and prominent role of β-strand swapping in organization of dUTPase oligomers E Takács, O Barabás, MV Petoukhov, DI Svergun, BG Vértessy FEBS letters 583 (5), 865-871	22	2009
Improving thermostability and catalytic activity of pyranose 2‐oxidase from Trametes multicolor by rational and semi‐rational design O Spadiut, C Leitner, C Salaheddin, B Varga, BG Vertessy, TC Tan, ... Febs Journal 276 (3), 776-792	22	2009
Keeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPases BG Vértessy, J Tóth Accounts of chemical research 42 (1), 97-106	103	2008
Experimental study on dUTPase-inhibitor candidate and dUTPase/disaccharide mixtures by PCS and ENS B Varga, F Migliardo, E Takacs, B Vertessy, S Magazù Journal of Molecular Structure 886 (1), 128-135	9	2008
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor B Varga, O Barabás, E Takács, N Nagy, P Nagy, BG Vértessy Biochemical and biophysical research communications 373 (1), 8-13	43	2008
Peptide conjugates of new in silico identified drug candidates and first/second line antituberculars-design, synthesis and antimycobacterial effect K Horvati, G Mezo, N Szabo, B Vertessy, B Varga, V Grolmusz, F Hudecz, ... JOURNAL OF PEPTIDE SCIENCE 14 (8), 161-161		2008
Neutron scattering studies on dUTPase complex in the presence of bioprotectant systems B Varga, F Migliardo, E Takacs, B Vertessy, S Magazù, C Mondelli Chemical Physics 345 (2), 250-258	21	2008
Methylene substitution at the α–β bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site J Kovári, O Barabás, B Varga, A Békési, F Tölgyesi, J Fidy, J Nagy, ... Proteins: Structure, Function, and Bioinformatics 71 (1), 308-319	28	2008
Amphiphilic nature of new antitubercular drug candidates and their interaction with lipid monolayer K Hill, CB Pénzes, BG Vértessy, Z Szabadka, V Grolmusz, É Kiss Colloids for Nano-and Biotechnology, 87-92	8	2008
Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme J Tóth, B Varga, M Kovács, A Málnási-Csizmadia, BG Vértessy Journal of Biological Chemistry 282 (46), 33572-33582	39	2007
Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase B Varga, O Barabás, J Kovári, J Tóth, É Hunyadi-Gulyás, É Klement, ... FEBS letters 581 (24), 4783-4788	43	2007
A novel fruitfly protein under developmental control degrades uracil-DNA A Békési, M Pukáncsik, V Muha, I Zagyva, I Leveles, E Hunyadi-Gulyás, ... Biochemical and biophysical research communications 355 (3), 643-648	13	2007
Fémek szerepe a fehérjeszerkezetben és-működésben= The role of metals in protein structure and function G Náray-Szabó, O Barabás, I Berente, A Czajlik, V Farkas, J Fidy, ... OTKA Kutatási Jelentések\| OTKA Research Reports		2007
Júlia Kovári BG Vértessy Budapest University of Technology and Economics		2007
Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins V Nemeth-Pongracz, O Barabas, M Fuxreiter, I Simon, I Pichová, ... Nucleic acids research 35 (2), 495-505	38	2007
Quantitative determination of uracil residues in Escherichia coli DNA: Contribution of ung, dug, and dut genes to uracil avoidance SU Lari, CY Chen, BG Vertéssy, J Morré, SE Bennett DNA repair 5 (12), 1407-1420	42	2006
INOR 451-Kinetic effects of vanadium compounds on human dUTPase, the enzyme responsible for DNA integrity and involved in cancer cell survival I Zagyva, O Barabas, J Smee, DC Crans, B Vertessy ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 232		2006
Characterization of the nuclease responsible for uracil-DNA signalling in drosophila melanogaster M Pukancsik, A Bekesi, F Felfoldi, I Zagyva, F Medzihradszky, G Vertessy FEBS JOURNAL 273, 114-114		2006
Cooperativity in human dUTPase homotrimer B Varga, J Kovari, O Barabas, E Takacs, A Malnasi-Csizmadia, ... FEBS JOURNAL 273, 192-192		2006
Puzzles in formation of trimeric dUTPases E Takacs, A Bekesi, B Vertessy FEBS JOURNAL 273, 309-309		2006
dUTpase MRNA silencing triggers apoptosis in cancer cells J Kovari, I Zagyva, G Merenyi, BG Vertessy FEBS JOURNAL 273, 113-113		2006
A new family of nucleases: the uracil-DNA-specific nuclease of pupating insects A Bekesi, F Felfoldi, M Pukancsik, V Maha, I Zagyva, I Leveles, ... FEBS JOURNAL 273, 53-53		2006
A retroviral dUTPase: modulatory effect of flexible segments on protein structure and function V Nemeth, O Barabas, M Fuxreiter, D Svergun, M Petoukhov, BG Vertessy FEBS JOURNAL 273, 312-312		2006
Interacting partners of M-PMV nucleocapsid-DUTPase V Németh-Pongrácz, J Snasel, M Rumlova, I Pichova, BG Vértessy Nucleosides, Nucleotides and Nucleic Acids 25 (9-11), 1197-1200	2	2006
Crystallization and preliminary X-ray studies of dUTPase from Mason–Pfizer monkey retrovirus O Barabás, V Németh, BG Vértessy Acta Crystallographica Section F: Structural Biology and Crystallization ...	12	2006
Synthesis of URACIL-DNA specific endonuclease derived peptides for generation of enzyme specific antibodies M Ligeti, A Bekesi, A Magyar, F Hudecz, BG Vertessy Journal of Peptide Science 12, 155-155		2006
Role of the C-terminal conserved sequence motif in the function of dutpase from Mason-Pfizer monkey retrovirus O Barabas, V Nemeth-Pongracz, A Magyar, F Hudecz, BG Vertessy Journal of Peptide Science 12, 206	2	2006
Same fold but altered responsivity in the evolution of dUTPase homotrimer E Takacs, O Barabas, D Svergun, Z Dubrovay, VK Grolmusz, B Vertessy FEBS JOURNAL 272, 100-100		2005
Uracil-DNA nuclease: protein enzyme possessing nuclease activity specific for uracil containing nucleic acid, process for its preparation and methods of use BG Vertessy, A Beke, F Felfoldi, VI Grolmusz, M Pukancsik US Patent App. 11/160,040	2	2005
Mechanistic studies of dUTPases J Kovári, T Imre, P Szabó, BG Vértessy Nucleosides, Nucleotides and Nucleic Acids 23 (8-9), 1475-1479	2	2004
Structural insights into the catalytic mechanism of phosphate ester hydrolysis by dUTPase O Barabás, V Pongrácz, J Kovári, M Wilmanns, BG Vértessy Journal of Biological Chemistry 279 (41), 42907-42915	72	2004
Experimental observation of the pentacovalent intermediate in dUTPase: structural snapshots along the reaction coordinate O Barábas, V Pongrácz, J Kovári, M Wilmanns, BG Vértessy Acta Crystallographica Section A: Foundations of Crystallography 60 (a1), 26-26		2004
A tradeoff between protein stability and conformational mobility in homotrimeric dUTPases E Takács, VK Grolmusz, BG Vértessy FEBS letters 566 (1), 48-54	28	2004
Developmental regulation of dUTPase in Drosophila melanogaster A Békési, I Zagyva, É Hunyadi-Gulyás, V Pongrácz, J Kovári, ÁO Nagy, ... Journal of Biological Chemistry 279 (21), 22362-22370	39	2004
Multidimensional NMR identifies the conformational shift essential for catalytic competence in the 60-kDa Drosophila melanogaster dUTPase trimer Z Dubrovay, Z Gáspári, É Hunyadi-Gulyás, KF Medzihradszky, A Perczel, ... Journal of Biological Chemistry 279 (17), 17945-17950	12	2004
Altered Active Site Flexibility and a Structural Metal-binding Site in Eukaryotic dUTPase KINETIC CHARACTERIZATION, FOLDING, AND CRYSTALLOGRAPHIC STUDIES OF THE HOMOTRIMERIC DROSOPHILA ENZYME J Kovári, O Barabás, E Takács, A Békési, Z Dubrovay, V Pongrácz, ... Journal of Biological Chemistry 279 (17), 17932-17944	37	2004
ORDERING OF THE'PEPTIDE-LIKE'C-TERMINUS OF DUTPASE UPON BINDING OF SUBSTRATE ANALOGUES: A HETERONUCLEAR NMR STUDY Z Dubrovay, Z Gaspari, A Perczel, BG Vertessy JOURNAL OF PEPTIDE SCIENCE 10, 223-223		2004
ENZYME CATALYSIS AND REGULATION-Multidimensional NMR Identifies the Conformational Shift Essential for Catalytic Competence in the 60-kDa Drosophila melanogaster dUTPase Trimer. Z Dubrovay, Z Gaspari, E Hunyadi-Gulyas, KF Medzihradszky, A Perczel, ... Journal of Biological Chemistry 279 (17), 17945-17950		2004
ENZYME CATALYSIS AND REGULATION-Altered Active Site Flexibility and a Structural Metal-binding Site in Eukaryotic dUTPase. KINETIC CHARACTERIZATION, FOLDING, AND CRYSTALLOGRAPHIC STUDIES OF THE J Kovari, O Barabas, E Takacs, A Bekesi, Z Dubrovay, V Pongracz, ... Journal of Biological Chemistry 279 (17), 17932-17944		2004
dUTPase and nucleocapsid polypeptides of the Mason-Pfizer monkey virus form a fusion protein in the virion with homotrimeric organization and low catalytic efficiency O Barabás, M Rumlová, A Erdei, V Pongrácz, I Pichová, BG Vértessy Journal of Biological Chemistry 278 (40), 38803-38812	22	2003
Catalytic and structural role of the metal ion in dUTP pyrophosphatase D Mustafi, A Bekesi, BG Vertessy, MW Makinen Proceedings of the National Academy of Sciences 100 (10), 5670-5675	38	2003
PROTEIN STRUCTURE AND FOLDING-dUTPase and Nucleocapsid Polypeptides of the Mason-Pfizer Monkey Virus Form a Fusion Protein in the Virion with Homotrimeric Organization and Low Catalytic Efficiency. O Barabas, M Rumlova, A Erdei, V Pongracz, I Pichova, BG Vertessy Journal of Biological Chemistry 278 (40), 38803-38812		2003
Characterization of conformational properties of protein/trehalose/water system by neutron scattering A Brandt, S Magazu, A Mangione, F Migliardo, BG Vertessy Applied Physics A 74 (1), s457-s458	1	2002
Conformational studies of poly (ethylene oxide) in crystalline, molten, and solution phase C Branca, S Magazu, G Maisano, F Migliardo, P Migliardo, G Romeo, ... Molecular Crystals and Liquid Crystals 372 (1), 17-23	1	2002
dUTPases: Essential factors in preventive DNA care-Preface BG Vertessy CURRENT PROTEIN & PEPTIDE SCIENCE 2 (4)	6	2001
Altered subunit communication in subfamilies of trimeric dUTPases A Fiser, BG Vértessy Biochemical and biophysical research communications 279 (2), 534-542	44	2000
A new potent calmodulin antagonist with arylalkylamine structure: crystallographic, spectroscopic and functional studies V Harmat, Z Böcskei, G Náray-Szabó, I Bata, AS Csutor, I Hermecz, ... Journal of molecular biology 297 (3), 747-755	39	2000
Pyruvate Kinase as a Microtubule Destabilizing Factorin Vitro BG Vértessy, D Bánkfalvi, J Kovács, P Löw, A Lehotzky, J Ovádi Biochemical and biophysical research communications 254 (2), 430-435	33	1999
Simultaneous binding of drugs with different chemical structures to Ca2+-calmodulin: crystallographic and spectroscopic studies BG Vertessy, V Harmat, Z Böcskei, G Náray-Szabó, F Orosz, J Ovádi Biochemistry 37 (44), 15300-15310	53	1998
The complete triphosphate moiety of non-hydrolyzable substrate analogues is required for a conformational shift of the flexible C-terminus in E. coli dUTP pyrophosphatase BG Vertessy, G Larsson, T Persson, AC Bergman, R Persson, PO Nyman FEBS letters 421 (1), 83-88	48	1998
Alternative Binding of Two Sequential Glycolytic Enzymes to Microtubules MOLECULAR STUDIES IN THE PHOSPHOFRUCTOKINASE/ALDOLASE/MICROTUBULE SYSTEM BG Vértessy, F Orosz, J Kovács, J Ovádi Journal of Biological Chemistry 272 (41), 25542-25546	68	1997
Flexible glycine rich motif of Escherichia coli deoxyuridine triphosphate nucleotidohydrolase is important for functional but not for structural integrity of the enzyme BG Vertessy Proteins: Structure, Function, and Bioinformatics 28 (4), 568-579	56	1997
The interaction of a new anti‐tumour drug, KAR‐2 with calmodulin F Orosz, BG Vértessy, C Salerno, C Crifo, E Capuozzo, J Ovádi British journal of pharmacology 121 (5), 955-962	22	1997
Interaction of a new bis‐indol derivative, KAR‐2 with tubulin and its antimitotic activity F Orosz, J Kovács, P Löw, BG Vértessy, Z Urbányi, T Ács, T Keve, J Ovádi British journal of pharmacology 121 (5), 947-954	27	1997
Crystallization and preliminary diffraction analysis of Ca2+‐calmodulin‐drug and apocalmodulin‐drug complexes BG Vertessy, Z Böcskei, V Harmath, G Náray‐Szabó, J Ovadi Proteins: Structure, Function, and Bioinformatics 28 (1), 131-134	7	1997
Characterization of microtubule-phosphofructokinase complex: specific effects of MgATP and vinblastine BG Vértessy, J Kovács, P Löw, A Lehotzky, A Molnár, F Orosz, J Ovádi Biochemistry 36 (8), 2051-2062	31	1997
Triosephosphate isomerase deficiency: predictions and facts F Orosz, BG Vértessy, S Hollán, M Horányi, J Ovádi Journal of theoretical biology 182 (3), 437-447	33	1996
Specific derivatization of the active site tyrosine in dUTPase perturbs ligand binding to the active site BG Vertessy, R Persson, AM Rosengren, M Zeppezauer, PO Nyman Biochemical and biophysical research communications 219 (2), 294-300	34	1996
Specific characteristics of phosphofructokinase-microtubule interaction BG Vértessy, J Kovács, J Ovádi FEBS letters 379 (2), 191-195	22	1996
Functional role of the C-terminal flexible arm of E. coli deoxyuridine triphosphatase BG Vertessy Progress in Biophysics and Molecular Biology, 219	1	1996
Anti-calmodulin potency of indol alkaloids in in vitro systems A Molnár, K Liliom, F Orosz, BG Vértessy, J Ovádi European Journal of Pharmacology: Molecular Pharmacology 291 (2), 73-82	24	1995
Identification of tyrosine as an active site residue involved in the catalytic mechanism of Escherichia coli dUTPase. BG Vertessy, M Zeppezauer Biochemical Society transactions 22 (2), 233S	4	1994
Identification of tyrosine as a functional residue in the active site of Escherichia coli dUTPase BG Vertessy, P Zalud, PO Nyman, M Zeppezauer Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular ...	29	1994
Metabolite channeling versus free diffusion: reinterpretation of aldolase-catalysed inactivation of glyceraldehyde-3-phosphate dehydrogenase. BG Vértessy, M Vas Biochemical Journal 286 (Pt 3), 977	3	1992
Modulation of the interaction between aldolase and glycerol-phosphate dehydrogenase by fructose phosphates BG Vértessy, F Orosz, J Ovádi Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular ...	14	1991
Elasticity of the human red cell membrane skeleton. Effects of temperature and denaturants. BG Vertessy, TL Steck Biophysical journal 55 (2), 255	82	1989
Transient-time analysis of substrate-channelling in interacting enzyme systems. J Ovádi, P Tompa, B Vértessy, F Orosz, T Keleti, GR Welch Biochem. J 257, 187-190	42	1989
The perfection of substrate-channelling in interacting enzyme systems: Energetics and evolution T Keleti, B Vértessy, GR Welch Journal of theoretical biology 135 (1), 75-83	6	1988
The control of cell metabolism for homogeneous vs. heterogeneous enzyme systems GR Welch, T Keleti, B Vértessy Journal of theoretical biology 130 (4), 407-422	37	1988
A simple approach to detect active‐site‐directed enzyme‐enzyme interactions B VÉRTESSY, J OVÁDI European Journal of Biochemistry 164 (3), 655-659	37	1987
Microenvironment of the enzyme-bound NADH is different in lobster and pig muscle glyceraldehyde-3-phosphate dehydrogenase microcrystals B Vértessy, M Vas, T Keleti Archives of biochemistry and biophysics 251 (1), 299-305	1	1986
Dynamics of Biochemical Systems T Keleti, B Vértessy, S Damjanovich, T Keleti, L Trón Symp. Biol. Hung. 30, 3	8	1986
Monday, February 22, 2010 309a G Rona, E Takacs, Z Bozoky, Z Kornyei, M Neubrandt, J Toth, I Scheer, ...
Relation of factors influencing genomic uracil appearance and Drosophila development A Horváth, V Muha, A Békési, M Pukáncsik, I Kiss, F Jankovics, M Erdélyi, ...
OLIGOMER STABILITY OF HOMOTRIMERIC DUTPASES OB EnikTakács, D Svergun, BG Vértessy
dUTPase is essential for genome stability and imaginal tissue development in Drosophila A Horváth, V Muha, A Békési, J Batki, B Hodoscsek, P Vilmos, F Jankovics, ...
Insights & Perspectives AN Kaczmarczyk, A Kopp, BT Lahn, SK Madathil, PT Nelson, KE Saatman, ... Hypothesis 23, 24
Ibolya Leveles, Veronika Kadar, Imre Zagyva, Abris Bendes, Gergely Rona, Kinga Nyiri, Veronika Nemeth, Judit Toth BG Vertessy Foundations of Crystallography
Angéla Beke BG Vértessy, A Erdei, G László
Structural description of enzymatic catalysis based on snapshots along the reaction coordinate O Barabás, V Pongrácz, J Kovári, A Popov, M Wilmanns, BG Vértessy
SYNTHESIS OF dUTPase DERIVED PEPTIDES FOR GENERATION OF ENZYME SPECIFIC ANTIBODIES M Ligeti, A Bekesi, A Magyar, F Hudecz, BG Vértessy
Evolution of dUTPase mechanism and structure O Barabás, A Popov, M Wilmanns, BG Vértessy
Effects of the metal cofactor in the dUTPase mechanism O Barabás, J Kovári, A Popov, M Wilmanns, BG Vértessy
Evolution of allosterism in dUTPase trimers E Takács, O Barabás, B Varga, BG Vértessy
STRUCTURE-FUNCTION STUDIES ON DUTPASES FOR KINETIC ANALYSIS AND INHIBITOR TESTING B Varga, BG Vértessy
Species-specific features of the dUTPase mechanism O Barabás, V Pongrácz, J Kovári, E Takács, A Popov, M Wilmanns, ...
Structure-function studies on dUTPase enzymes. Mechanism of a preventive DNA-repair enzyme. O Barabás, ZS Dubrovay, BG Vértessy
EMBO/HHMI Meeting, Budapest, 2005 V Muha, BG Vértessy

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